i. Clear data
Click the icon or cRF Calculator
name to clear all data and start afresh.
ii. Select blood group
Blood group A is selected by default. Click on the blood group name to select a different one.
iii. Select antibody specificities
Click antigen names to toggle between selected and deselected states. Selected antigens are highlighted in blue.
Click locus names to cycle through three states: 'original' (the initial selection), 'all unchecked' (deselects all), and 'all checked' (selects all).
iv. Matchability calculation
HLA-B and DRB1 types are required for matchability. Select from the drop-down lists. For homozygous types,
select the same specificity twice or select one and leave the other blank.
v. Donor cohort selection
A uses the all-10,000-donor reference calculation,
aligned with the current ODT workbook and intentionally retaining known upstream behaviour. Only 3,642 donors are DP typed;
D is a non-official subset analysis using those
records. Because the published matchability bands apply to the full cohort, matchability and favourable donor
values are not applicable to the DP-typed subset and are saved/exported as blank values.
vi. Shareable URLs
The calculator restores state from query parameters in the page URL. Supported parameters are
bg, specs, recip_hla, and donor_set, for example
?bg=O&specs=A1,B7&recip_hla=B44,DR7&donor_set=1. Open that URL to restore the
blood group, selected specificities, recipient HLA-B/DR types, and donor cohort.
vii. Selected specs
Copy selected specificities to clipboard by clicking
. This copies text without formatting.
Double click any specificity to remove it.
viii. Manual specs input
Type or paste antigens separated by spaces, commas, or tabs (Excel compatible). Input is case insensitive.
CWn and DPBn can be input as Cn, DPn, or DPB1*n. Press enter to process.
ix. Click Matches
to view a table showing donor availability at each matching level (HLA matching grade).
x. Profile collection
Click Add
to save current results and their calculation mode, canonical recipient HLA, and data provenance to memory.
Red badge shows saved count. Click
Copy to export as tab separated values (.tsv)
format for Excel/analysis tools.
